Name Hussain Ismaeel
Title Chair of Medical Services
Primary Specialty Cardiology Consultant
Languages Arabic & English
Contact Details
Email [email protected]
Phone +974 4400 4400

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  • Validation Of The Arabic Version Of The Minnesota Living With Heart Failure Questionnaire.Zahwe M, Isma’eel H, Skouri H, Al-Hajje A, Rachidi S, Tamim H, Noureddine S Heart & Lung : The Journal Of Critical Care. 2020, vol.49, no.1, pp-36-41
  • Out-Of-Hospital Cardiopulmonary Resuscitation: A Position Statement Of The Lebanese Society Of Cardiology And The Lebanese Society Of Emergency Medicine. Isma’eel H, Noureddine S, Mohammad M, Zgheib A, Abou Arbid S, Njeim M, Nasr S, Bassil R, Sarkis A, Abi Saleh B, El Sayed M Cardiovascular Diagnosis And Therapy. 2019, vol.9, no.6, pp-609-612
  • The Association Of Water-Pipe Smoking And coronary Artery Calcium In A Community-Based Sample. Chami HA, Isma’eel H, Tamim H, Adawi M, Al Kuwari M, Al Mullah A Chest. 2019, vol.155, no.6, pp-1217-1225
  • Sleepless In Beirut: Sleep Difficulties In An Urban Environment With Chronic Psychosocial Stress. Chami HA, Bechnak A, Isma’eel H, Talih F, Nasreddine L, Nasrallah M, Tamim H Journal Of Clinical Sleep Medicine : Jcsm : Official Publication Of The American Academy Of Sleep Medicine. 2019, vol.15, no.4, pp-603-614
  • High Precision Digitization Of Paper-Based Ecg Records: A Step Toward Machine Learning. Baydoun M, Safatly L, Abou Hassan OK, Ghaziri H, El Hajj A, Isma’eel H Ieee Journal Of Translational Engineering In Health And Medicine. 2019, vol.7, pp-1900808
  • Worsening Of The Cardiovascular Profile In A Developing Country: The Greater Beirut Area Cardiovascular Cohort. Isma’eel HA, Almedawar MM, Breidy J, Nasrallah M, Nakhoul N, Mouneimne Y, Nasreddine L, Khoueiry-Zgheib N, Abiad M, Tamim H Global Heart. 2018, vol.13, no.4, pp-275-283
  • Noninvasive Multimodality Imaging For The Diagnosis Of Constrictive Pericarditis. Alajaji W, Xu B, Sripariwuth A, Menon V, Kumar A, Schleicher M, Isma’eel H, Cremer PC, Bolen MA, Klein AL Circulation. Cardiovascular Imaging. 2018, vol.11, no.11, pp-e007878
  • Artificial Neural Network-Based Model Enhances Risk Stratification And Reduces Non-Invasive Cardiac Stress Imaging Compared To Diamond-Forrester And Morise Risk Assessment Models: A Prospective Study. Isma’eel HA, Sakr GE, Serhan M, Lamaa N, Hakim A, Cremer PC, Jaber WA, Garabedian T, Elhajj I, Abchee AB Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology. 2018, vol.25, no.5, pp-1601-1609
  • Resuscitation Of Out-Of-Hospital Cardiac Arrest Victims In Lebanon: The Experience And Views Of Prehospital Providers. Haidar MH, Noureddine S, Osman M, Isma’eel H, El Sayed M Journal Of Emergencies, Trauma, And Shock. 2018, vol.11, no.3, pp-183-188
  • Impact Of A Hospital-Based Educational Intervention On Dietary Salt-Related Knowledge And Behaviour In A Cardiac Care Unit Population In Lebanon. Walsh JL, Aridi H, Fathallah J, Al-Shaar L, Alam S, Nasreddine L, Isma’eel H Cardiovascular Diagnosis And Therapy. 2018, vol.8, no.2, pp-146-155
  • An Outflow Boundary Condition Model For Noninvasive Prediction Of Fractional Flow Reserve In Diseased Coronary Arteries. Fayssal IA, Moukalled F, Alam S, Isma’eel H Journal Of Biomechanical Engineering. 2018, vol.140, no.4
  • Short Telomere Length Is Associated With Aging, Central Obesity, Poor Sleep And Hypertension In Lebanese Individuals. Zgheib NK, Sleiman F, Nasreddine L, Nasrallah M, Nakhoul N, Isma’eel H, Tamim H Aging And Disease. 2018, vol.9, no.1, pp-77-89
  • A Minimally Processed Dietary Pattern Is Associated With Lower Odds Of Metabolic Syndrome Among Lebanese Adults. Nasreddine L, Tamim H, Itani L, Nasrallah MP, Isma’eel H, Nakhoul NF, Abou-Rizk J, Naja F Public Health Nutrition. 2018, vol.21, no.1, pp-160-171
  • Disparity In Spatial Distribution Of Pericardial Calcifications In Constrictive Pericarditis. Senapati A, Isma’eel HA, Kumar A, Ayache A, Ala CK, Phelan D, Schoenhagen P, Johnston D, Klein AL Open Heart. 2018, vol.5, no.2, pp-e000835
  • Prevalence, Awareness, And Control Of Hypertension In Greater Beirut Area, Lebanon. Noubani A, Nasreddine L, Sibai AM, Tamim H, Isma’eel H International Journal Of Hypertension. 2018, vol.2018, pp-5419861
  • Prevalence Of Diabetes In Greater Beirut Area: Worsening Over Time. Nasrallah MP, Nakhoul NF, Nasreddine L, Mouneimne Y, Abiad MG, Ismaeel H, Tamim H Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists. 2017, vol.23, no.9, pp-1091-1100
  • Myocardial Infarction Masquerading As Myocarditis In A Patient With Factor V Leiden: Unmasked With Mr. Walsh JL, Harris BHL, Gharzuddine W, Isma’eel H Bmj Case Reports. 2017, vol.2017
  • Normalization Of Biventricular Strain Post Steroid Treatment Of Effusive Constrictive Pericarditis. Walsh JL, Lamaa N, Alam S, Didi A, Isma’eel H Journal Of Cardiology Cases. 2017, vol.15, no.5, pp-167-169
  • Waterpipe Smoking And Risk Of Coronary Artery Disease. Almedawar MM, Walsh JL, Isma’eel HA* Current Opinion In Cardiology. 2016, vol.31, no.5, pp-545-50
  • Assessing Level of Agreement for Atherosclerotic Cardiovascular Disease Risk Categorization Between Coronary Artery Calcium Score and the American College of Cardiology/American Heart Association Cardiovascular Prevention Guidelines and the Potential Impact on Treatment Recommendations. Isma’eel H, Min D, Al-Shaar L, Hachamovitch R, Halliburton S, Gentry J, Griffin B, Schoenhagen P, Phelan D The American Journal Of Cardiology. 2016
  • An Attempt To Halt The Ever-Increasing Prevalence Of Morbidities Resulting From Excess Dietary Sodium Intake. The Lebanese Experience. Almedawar MM, Isma’Eel HA, Nasreddine L, Olabi A, Badr KF, Arnaout MS Le Journal Medical Libanais. The Lebanese Medical Journal. 2016, vol.64, no.2, pp-63-64
  • Assessment Of Cardiopulmonary Resuscitation Practices In Emergency Departments For Out-Of-Hospital Cardiac Arrest Victims In Lebanon. Noureddine S, Avedissian T, Isma’eel H, El Sayed MJ Journal Of Emergencies, Trauma, And Shock. 2016, vol.9, no.3, pp-115-21
  • Assessment Of Cardiopulmonary Resuscitation Practices In Emergency Departments For Out-Of-Hospital Cardiac Arrest Victims In Lebanon Noureddine S., Avedissian T., Isma’Eel H., El Sayed M.J. Journal Of Emergencies, Trauma And Shock. 2016, vol.9, no.3, pp-115-121
  • Artificial Neural Network Modeling Enhances Risk Stratification And Can Reduce Downstream Testing For Patients With Suspected Acute Coronary Syndromes, Negative Cardiac Biomarkers, And Normal Ecgs. Isma’eel HA, Cremer PC, Khalaf S, Almedawar MM, Elhajj IH, Sakr GE, Jaber WA The International Journal Of Cardiovascular Imaging. 2016, vol.32, no.4, pp-687-96
  • Diamond-Forrester And Morise Risk Models Perform Poorly In Predicting Obstructive Coronary Disease In Middle Eastern Cohort. Isma’eel HA, Serhan M, Sakr GE, Lamaa N, Garabedian T, Elhajj I, Skouri H, Abchee A International Journal Of Cardiology. 2016, vol.203, pp-803-5
  • An Attempt To Halt The Ever-Increasing Prevalence Of Morbidities Resulting From Excess Dietary Sodium Intake The Lebanese Experience Almedawar M.M., Isma’eel H.A., Nasreddine L., Olabi A., Badr K.F., Arnaout M.S. Journal Medical Libanais. 2016, vol.64, no.2, pp-63-64
  • Discordant Electrocardiogram Left Ventricular Wall Thickness And Strain Findings In Influenza Myocarditis. Hawwa N, Popovic ZB, Isma’eel HA*Echocardiography (Mount Kisco, N.Y.). 2015, vol.32, no.12, pp-1880-4
  • Quantifying The Impact Of Using Coronary Artery Calcium Score For Risk Categorization Instead Of Framingham Score Or European Heart Score In Lipid Lowering Algorithms In A Middle Eastern Population. Isma’eel HA, Almedawar MM, Harbieh B, Alajaji W, Al-Shaar L, Hourani M, El-Merhi F, Alam S, Abchee A Journal Of The Saudi Heart Association. 2015, vol.27, no.4, pp-234-43
  • Mixture Of Ischemia And Hibernation In A Patient With Severe Diagonal Disease: Value Of Perfusion And Metabolic Pet Imaging. Harb S, Ismaeel H, Bassiouny M, Jaber WA Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology. 2015, vol.22, no.5, pp-1155-7
  • Artificial Neural Network Modeling Using Clinical And Knowledge Independent Variables Predicts Salt Intake Reduction Behavior. Isma’eel HA, Sakr GE, Almedawar MM, Fathallah J, Garabedian T, Eddine SB, Nasreddine L, Elhajj IH Cardiovascular Diagnosis And Therapy. 2015, vol.5, no.3, pp-219-28
  • Sodium Intake Reduction Efforts In Lebanon. Almedawar MM, Nasreddine L, Olabi A, Hamade H, Awad E, Toufeili I, Arnaout S, Isma’eel HA* Cardiovascular Diagnosis And Therapy. 2015, vol.5, no.3, pp-178-85
  • Salt Intake Reduction Efforts: Advances And Challenges. Isma’eel H, Schoenhagen P, Webster J Cardiovascular Diagnosis And Therapy. 2015, vol.5, no.3, pp-169-71
  • Appropriateness And Diagnostic Yield Of Cardiac Magnetic Resonance Imaging From A Tertiary Referral Center In The Middle East. AlJaroudi W, Isma’eel H, El Merhi F, Assad T, Hourani M Cardiovascular Diagnosis And Therapy. 2015, vol.5, no.2, pp-88-97
  • Consumer Knowledge, Attitudes And Salt-Related Behavior In The Middle-East: The Case Of Lebanon Nasreddine L., Akl C., Al-Shaar L., Almedawar M.M., Ismaeel H.* Nutrients. 2014, vol.6, no.11, pp-5079-5102
  • Lifetime Cumulative Exposure To Waterpipe Smoking Is Associated With Coronary Artery Disease. Sibai AM, Tohme RA, Almedawar MM, Itani T, Yassine SI, Nohra EA, Isma’eel HA* Atherosclerosis. 2014, vol.234, no.2, pp-454-60
  • Improved Accuracy Of Anticoagulant Dose Prediction Using A Pharmacogenetic And Artificial Neural Network-Based Method. Isma’eel HA, Sakr GE, Habib RH, Almedawar MM, Zgheib NK, Elhajj IHEuropean Journal Of Clinical Pharmacology. 2014, vol.70, no.3, pp-265-73
  • Foreword: A Special Issue On The Prevention And Diagnosis Of Cardiovascular Disease Isma’eel H., Refaat M. Journal Medical Libanais. 2014, vol.62, no.2
  • Discrepancies Between Two Lipid-Lowering Guidelines For Cvd Prevention In Seemingly Healthy Individuals-Case Study Lebanon. Isma’eel HA, Harbieh B, Tamim H, Nasreddine L, Naja F, Sibai A, Adra N, Badr K, Hwalla N Cardiovascular Diagnosis And Therapy. 2013, vol.3, no.3, pp-129-36
  • Impact Of Coronary Artery Calcium Progression And Statin Therapy On Clinical Outcome In Subjects With And Without Diabetes Mellitus. Kiramijyan S, Ahmadi N, Isma’eel H, Flores F, Shaw LJ, Raggi P, Budoff MJ The American Journal Of Cardiology. 2013, vol.111, no.3, pp-356-61
  • I-COMBINE study: assessment of efficacy and safety profile of irbesartan/amlodipine fixed-dose combination therapy compared with amlodipine monotherapy in hypertensive patients uncontrolled with amlodipine 5 mg monotherapy: a multicenter, phase III, prospective, randomized, open-label with blinded-end point evaluation study. Bobrie G Clinical Therapeutics. 2012, vol.34, no.8, pp-1705-19
  • Prevalence And Non-Invasive Predictors Of Left Main Or Three-Vessel Coronary Disease: Evidence From A Collaborative International Meta-Analysis Including 22 740 Patients. D’Ascenzo F, Presutti DG, Picardi E, Moretti C, Omedè P, Sciuto F, Novara M, Yan AT, Goodman S, Mahajan N, Kosuge M, Palazzuoli A, Jong GP, Isma’eel H, Budoff MJ, Rubinshtein R, Gewirtz H, Reed MJ, Theroux P, Biondi-Zoccai G, Modena MG, Sheiban I, Gaita F Heart (British Cardiac Society). 2012, vol.98, no.12, pp-914-9
  • ‘longitudinal’ Topics In Cardiovascular Diagnosis And Therapy (Cdt). Schoenhagen P, Isma’eel H, Mocumbi AO Cardiovascular Diagnosis And Therapy. 2012, vol.2, no.2, pp-83-4
  • The Public Cost Of 3 Statins For Primary Prevention Of Cardiovascular Events In 7 Middle East Countries: Not All Of Them Can Afford It. Isma’eel H, Mohanna Z, Hamadeh G, Alam E, Badr K, Alam S, Rebeiz A International Journal Of Cardiology. 2012, vol.155, no.2, pp-316-8
  • Assessment Of Progression Of Coronary Atherosclerosis Using Multidetector Computed Tomography Angiography (Mdct). Hamirani YS, Kadakia J, Pagali SR, Zeb I, Isma’eel H, Ahmadi N, Sarraf G, Choi T, Patel A, Budoff MJ International Journal Of Cardiology. 2011, vol.149, no.2, pp-270-4
  • Impaired Aortic Distensibility Measured By Computed Tomography Is Associated With The Severity Of Coronary Artery Disease. Ahmadi N, Nabavi V, Hajsadeghi F, Flores F, Azmoon S, Ismaeel H, Shavelle D, Mao SS, Ebrahimi R, Budoff MJ The International Journal Of Cardiovascular Imaging. 2011, vol.27, no.3, pp-459-69
  • Normalization Of Automatic Plaque Quantification In Cardiac Computed Tomography (Cct). Hamirani YS, Zeb I, Pagali SR, Kadakia J, Saraff G, Choi T, Ahmadi N, Isma’eel H, Budoff MJ International Journal Of Cardiology. 2011, vol.146, no.2, pp-282-90
  • Diabetes Supersedes Dobutamine Stress Echocardiography In Predicting Cardiac Events In Female Patients Isma’eel H., Shamseddeen W., El Khoury M., Dimassi A., Nasrallah A., Arnaout M.S. Clinical And Experimental Obstetrics And Gynecology. 2010, vol.37, no.3, pp-197-200
  • The Diagnostic Accuracy Of 64-Detector Cardiac Computed Tomography Compared With Stress Nuclear Imaging In Patients Undergoing Invasive Cardiac Catheterization. Hamirani YS, Isma’eel H, Larijani V, Drury P, Lim W, Bevinal M, Saeed A, Ahmadi N, Karlsberg RP, Budoff MJ Journal Of Computer Assisted Tomography. 2010, vol.34, no.5, pp-645-51
  • Detection Of Aortic Regurgitation With 64-Slice Multidetector Computed Tomography (Mdct). Zeb I, Hamirani YS, Mao S, Isma’eel H, Saeed A, Karnwal S, Raina S, Chung J, Budoff MJ Academic Radiology. 2010, vol.17, no.8, pp-1006-11
  • A Computed Tomography Iron Index. Isma’eel H, Musallam KM, Budoff M, Taher AT European Journal Of Radiology. 2010, vol.75, no.2, pp-189-90
  • Determinants Of Left Main Calcifications In A Cohort Of 2136 Diabetes Patients. Isma’eel H, Hamirani YS, Daga N, Kadakia J, Mao S, Ahmadi N, Budoff MJ International Journal Of Cardiology. 2010, vol.142, no.3, pp-e48-50
  • Association Of Plaque In The Carotid And Coronary Arteries, Using Mdct Angiography. Hamirani YS, Larijani V, Isma’eel H, Pagali SR, Bach P, Karlsberg RP, Budoff MJ Atherosclerosis. 2010, vol.211, no.1, pp-141-5
  • Effect Of Obesity On Coronary Artery Plaque Using 64 Slice Multidetector Cardiac Computed Tomography Angiography. Isma’eel H, Tellalian D, Hamirani YS, Kadakia J, Nasir K, Budoff MJ International Journal Of Cardiology. 2010, vol.140, no.3, pp-358-60
  • Bilateral Elevated Hemidiaphragms With Visible Compression Of The Heart. Hamirani YS, Isma’eel H, Budoff MJ Texas Heart Institute Journal / From The Texas Heart Institute Of St. Luke’s Episcopal Hospital, Texas Children’s Hospital. 2010, vol.37, no.2, pp-248-9
  • Optimal Phase For Coronary Interpretations And Correlation Of Ejection Fraction Using Late-Diastole And End-Diastole Imaging In Cardiac Computed Tomography Angiography: Implications For Prospective Triggering. Isma’eel H, Hamirani YS, Mehrinfar R, Mao S, Ahmadi N, Larijani V, Nair S, Budoff MJ The International Journal Of Cardiovascular Imaging. 2009, vol.25, no.7, pp-739-49
  • Myocardial Infarction In A 28-Year-Old Thalassemia Intermedia Patient. El Rassi FA, Ismaeel HA, Koussa SC, Taher AT Clinical And Applied Thrombosis/Hemostasis : Official Journal Of The International Academy Of Clinical And Applied Thrombosis/Hemostasis. 2009, vol.15, no.4, pp-467-9
  • Ventricular Late Potentials Among Thalassemia Patients Isma’eel H., Shamseddeen W., Taher A., Gharzuddine W., Dimassi A., Alam S., Masri L., Khoury M. International Journal Of Cardiology. 2009, vol.132, no.3, pp-453-455
  • Survival And Complications Of Beta-Thalassemia In Lebanon: A Decade’s Experience Of Centralized Care. Charafeddine K, Isma’eel H, Charafeddine M, Inati A, Koussa S, Naja M, Taher A Acta Haematologica. 2008, vol.120, no.2, pp-112-6
  • Underutilization Of Venous Thromboemoblism Prophylaxis In Medical Patients In A Tertiary Care Center Masroujeh R., Shamseddeen W., Isma’eel H., Otrock Z.K., Khalil I.M., Taher A. Journal Of Thrombosis And Thrombolysis. 2008, vol.26, no.2, pp-138-141
  • Correlation Of Liver Iron Concentration Determined By R2 Magnetic Resonance Imaging With Serum Ferritin In Patients With Thalassemia Intermedia. Taher A, El Rassi F, Isma’eel H, Koussa S, Inati A, Cappellini MD Haematologica. 2008, vol.93, no.10, pp-1584-6
  • Relation Between Iron-Overload Indices, Cardiac Echo-Doppler, And Biochemical Markers In Thalassemia Intermedia. Isma’eel H, Chafic AH, El Rassi F, Inati A, Koussa S, Daher R, Gharzuddin W, Alam S, Taher A The American Journal Of Cardiology. 2008, vol.102, no.3, pp-363-7
  • Complications Of Beta-Thalassemia Intermedia: A 12-Year Lebanese Experience. Taher A, El Rassi F, Ismaeel H, Inati A American Journal Of Hematology. 2008, vol.83, no.7, pp-605-6
  • Stroke In Thalassemia: A Dilemma. Taher A, Mehio G, Isma’eel H, Cappellini MD American Journal Of Hematology. 2008, vol.83, no.4, pp-343
  • Chronic Transfusion, Iron Overload And Cardiac Dysfunction: A Multi-Dimensional Perspective Isma’eel H., Cappellini M.D., Taher A. British Journal Of Cardiology. 2008, vol.15, no.1, pp-40-46
  • Sickle Cell Disease: The Lebanese Experience. Inati A, Jradi O, Tarabay H, Moallem H, Rachkidi Y, El Accaoui R, Isma’eel H, Wehbe R, Mfarrej BG, Dabbous I, Taher A International Journal Of Laboratory Hematology. 2007, vol.29, no.6, pp-399-408
  • Anticoagulation Clinics Are Needed In Developing Countries. Isma’eel H, Zebian R, El-Accaoui R, Dimassi A, Rashid K, Alam S, Taher A, Khoury M, Arnaout MS International Journal Of Cardiology. 2007, vol.115, no.3, pp-410-1
  • Prevalence Of Variety Of Cardiac Tumors Presenting To Tertiary Care Center In Eastern Mediterranean Area Over 21 Years. Isma’eel H, Abdelbaki K, Obeid M, Arnaout MS International Journal Of Cardiology. 2007, vol.114, no.1, pp-121-2
  • A Review Of The Off-Label Use Of Recombinant Activated Factor Vii In A Developing Country Tertiary Care Center. El Accaoui R, Isma’eel H, Khalil PB, Taher A Blood Coagulation & Fibrinolysis : An International Journal In Haemostasis And Thrombosis. 2006, vol.17, no.8, pp-647-50
  • Saecg Parameters And Left Ventricular Chamber Sizes: Lesson From Anemia Conditions In Thalassemia Major Patients Isma’eel H., Taher A., Shamseddeen W., Khoury M., Gharzuddine W., Arnaout M.S., Alam S. International Journal Of Cardiology. 2006, vol.113, no.3
  • Screening For Inherited Thrombophilia Might Be Warranted Among Eastern Mediterranean Sickle-ßeta-0 Thalassemia Patients Isma’eel H., Arnaout M.S., Shamseddeen W., Mahfouz R., Zeineh N., Jradi O., Taher A. Journal Of Thrombosis And Thrombolysis. 2006, vol.22, no.2, pp-121-123
  • Beta-Thalassemia: The Lebanese Experience. Inati A, Zeineh N, Isma’eel H, Koussa S, Gharzuddine W, Taher A Clinical And Laboratory Haematology. 2006, vol.28, no.4, pp-217-27
  • Thalassemia Intermedia: Revisited. Taher A, Isma’eel H, Cappellini MD Blood Cells, Molecules & Diseases. 2006, vol.37, no.1, pp-12-20
  • Genetic Thrombophilia In Patients With Vte In Eastern Mediterranean Located Tertiary Care Center; Is It Time To Change The Algorithm For Thrombophilia Work Up Decision Making? Isma’eel H., El Accaoui R., Shamseddeen W., Taher A., Alam S., Mahfouz R., Arnaout M.S. Journal Of Thrombosis And Thrombolysis. 2006, vol.21, no.3, pp-267-270
  • Massive Pulmonary Embolism In A Lebanese Patient Doubly Heterozygous For Mthfr And Factor V Leiden Presenting With Syncope And Treated With Tenecteplase Isma’eel H., Taher A., Alam S., Arnaout M.S. Journal Of Thrombosis And Thrombolysis. 2006, vol.21, no.2, pp-179-184
  • Diastolic Dysfunction And Pulmonary Hypertension In Sickle Cell Anemia: Is There A Role For L-Carnitine Treatment? El-Beshlawy A, Abd El Raouf E, Mostafa F, Talaat M, Isma’eel H, Aoun E, Hoffbrand AV, Taher A Acta Haematologica. 2006, vol.115, no.1-2, pp-91-6
  • Apoptosis In Thalassemia Major Reduced By A Butyrate Derivative. El-Beshlawy A, Seoud H, Ibrahim A, Youssry I, Gabre H, Isma’eel H, Aoun E, Taher A Acta Haematologica. 2005, vol.114, no.3, pp-155-9